Natalia Rocon
Published in October 27, 2020

Niacin and Triglycerides: What You Need To Know

Niacin also called vitamin B3 is found in turkey, red meat, chicken, grains, and beans.

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By Natalia Rocon

t is a fundamental nutrient of the human body and it helps improve bloodstream levels of triglycerides, high-density lipoprotein (HDL), and low-density lipoprotein. This type of vitamin plays a fundamental role in hormone synthesis, energy production, and gene expression. When using niacin to control triglycerides, the amount you are advised to take depends on your ability to tolerate the drug’s side effects and current levels in your system.

The Relationship between Niacin and Triglycerides

When your body has triglycerides and low-density lipoprotein (bad cholesterol), they accumulate in the arteries, decrease your blood flow, and put you at a higher risk of developing cardiovascular disease. It’s the high-density lipoprotein (good cholesterol), that is left with the role of removing the two above from your bloodstream. If this fails, then taking niacin becomes the number one recommendation from your doctor. This vitamin will boost the HDL levels by about 20 to 35%, reduce triglycerides by 30%., reduce LDL levels by about 5-26%, and significantly reduce levels of the very-low-density lipoprotein (VLDL).

To keep your diet healthy, take 14 mg to 16 mg of niacin from tuna, beef, peanuts, and other natural sources daily. A doctor may recommend a mega-dose ranging between 100mg and 2000mg daily so as to reduce triglycerides in your system. The natural way of reducing triglycerides by 20% is by taking a low sugar and low-fat diet. Doing a two and a half hour moderate exercise on weekly basis reduces these proteins by about 20-30%.

How the Elimination of Triglycerides Takes Place

First, the presence of niacin in your system hinders the release of fatty acids from your body’s fat cells. This means very few fatty acids get to reach the liver. This causes a significant reduction in the number of VLDL particles. It’s this less VLDL that causes a reduction in LDL and increases the levels of HDL. With the increased levels of HDL, your body can now fight to reduce triglycerides levels in your system.

Whether you are taking the crystalline/Immediate-release niacin or the Extended-release niacin, the benefits are the same. In the former, the niacin in the tablet is released immediately after you take this tablet and so it’s advisable to start with smaller doses then increase it with time. In the latter, you will feel the flush but the intensity is reduced.


When taken orally, this drug causes flushing of one’s skin. Also, you need to avoid an overdose of this drug because it can damage your liver and increase your chances of suffering a stroke. Do not take the immediate-release dose more than two times a day. It is risky and unsafe for you.


Niacin is most effective when taken with fish oil and it’s safer when you expose your liver to it just for a few hours. It is therefore advisable to take this drug orally after you have been tested and you are sure your triglycerides levels are higher. Nevertheless, you have to ensure you follow the dosage as advised by a reputable doctor. Over the counter, purchases can be a great source of health risks for you.

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